Category: Hematology. Federated access using single sign-on credentials. PROMACTA (eltrombopag) Tablets contain Eltrombopag olamine, a small molecule thrombopoietin (TPO) receptor agonist for oral administration. Geriatric Use: Of the 106 patients in two randomized clinical trials of Eltrombopag 50 mg in chronic ITP, 22% were 65 years of age and over, while 9% were 75 years of age and over. Product Name. About REVOLADE (eltrombopag olamine). Description ; Reviews (0) Indications. Description: IC50 Value: 0.27 uM (EC50 in murine BAF3 cells) [1] Eltrombopag is a new, orally active thrombopoietin-receptor (c-mpl) agonist that stimulates thrombopoiesis. DescriptionEltrombopag olamine.png. Promacta (eltrombopag) is known as Revolade outside the U.S. and is marketed worldwide by Novartis. Drug Prior Authorization Form Revolade (eltrombopag olamine). Home Products Eltrombopag Eltrombopag Olamine. The safety and efficacy ofEltrombopag in pediatric patients younger than 1 year with ITP have not yet been established. Eltrombopag Olamine - 25mg. Closely monitor platelet counts. RESPONSE, 2019 Novartis | Use of this website is subject to our, This is an international site for REVOLADE, See what ASH has to say about COVID-19 and ITP, See what ASH has to say about COVID-19 and Aplastic Anemia, REVOLADE Product Renal Impairment: No adjustment in the initial dose of Eltrombopag is needed for patients with renal impairment. Brand Name: Elopag 50 Pack Size: 14 Tab Manufacturer: Everest Pharmaceuticals Ltd. Eltrombopag Olamine 50 mg quantity. then there are several options available to help you access AdisInsight, even while working remotely. eltrombopag olamine. Eltrombopag Olamine is indicated in Chronic Immune (Idiopathic) Thrombocytopenia, Chronic Hepatitis C-associated Thrombocytopenia, Severe Aplastic Anemia. 50 answered questionsAsk a question. L.A. Care's Medi-Cal Plan covers generic and brand name drugs. Unlike recombinant TPO or romiplostim, Eltrombopag does not activate the AKT pathway in any way. The information on the site is not country-specific, and may Your email address will not be shared without your permission. Eltrombopag was discovered as a result of . Eltrombopag received breakthrough therapy designation from the U.S. Food and Drug Administration (FDA) in February 2014, for people with aplastic anemia for which immunosuppression has not been successful. CAT#: E24518. reg Address. IMPORTANT: The information on this website is Generic : Eltrombopag. Brand name: Promacta. Product Description. How To Increase Your Platelet Count In A Natural Way? REVOLADE is the TPO-RA proven in the most disease states 1 REVOLADE is indicated for the treatment of: Patients aged 1 year and above with primary immune thrombocytopenia (ITP) lasting 6 months or longer from diagnosis and who are refractory to other treatments (eg, corticosteroids, immunoglobulins) I can't have lactose or soy. Eltrombopag is also used to increase the number of platelets in people who have hepatitis C (a viral infection that may damage the liver) so that they can begin and continue treatment with interferon (Peginterferon, Pegintron, others) and ribavirin (Rebetol). How should this medicine be used? Eltrombopag olamine a type of thrombopoietin receptor agonist and is used to treat thrombocytopenia (a lower-than-normal number of platelets in the blood) in patients with chronic immune thrombocytopenic purpura (a condition in which platelets are destroyed by the immune system). China Eltrombopag Olamine Manufacture, Visit Here to Find the Eltrombopag Olamine That You are Searching for. Keywords : Eltrombopag Olamine. 0/5.0 (: 0). Generic Name. We know that you, and your patients, are looking for answers. In one report, a subject who ingested 5,000 mg of Eltrombopag had a platelet count increase to a maximum of 929 x 109/L at 13 days following the ingestion. Wong RSM, Saleh MN, Khelif A, et al. It is under investigation as a platelet growth factor given orally for the Erythropoietin for clinical use is produced by recombinant DNA technology and the name epoetin is often applied to such materi-al. Eltrombopag should not be used to treat people who have low numbers of platelets due to conditions other than ITP, hepatitis C, or aplastic anemia. stem cell transplantation. Websites. . Purity by HPLC : 95. US FDA: Eltrombopag [13]. 11.5. located. Eltrombopag olamine | C29H36N6O6 | CID 135449331 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological . Eltrombopag olamine. Chronic Immune (Idiopathic) Thrombocytopenia-, Chronic Hepatitis C-associated Thrombocytopenia-, * '. Eltrombopag olamine, a thrombopoietin receptor (TpoR) agonist, was approved in late 2008 for the once-daily, oral short-term and long-term treatment of adult patients with previously treated chronic idiopathic thrombocytopenic purpura (ITP). Potential advantages of eltrombopag may include a sustained platelet response and. Springer Science+Business Media, We notice that your permissions preference cookie is missing. ZenHeal wellness Private Limited. A link to download a PDF version of the drug profile will be included in your email receipt. Characteristics, I am a Health Care Eltrombopag Olamine. Pediatric Patients with ITP Aged 1 to 5 Years: Initiate Eltrombopag at a dose of 25 mg once daily. Brand Name Dosage Form Strength Company Pack Size & Price; Cytopag Tablet 50 mg ACI Limited Unit . Please refer to our, French Innovative Leukemia Organisation; GlaxoSmithKline; Groupe Francophone des Myelodysplasies; Novartis; Technische Universitat Dresden, Antianaemics; Antineoplastics; Benzoates; Biphenyl compounds; Carboxylic acids; Hydrazines; Pyrazoles; Radioprotectives; Small molecules, Yes eltrombopag systemic Brand name: Promacta Drug class: platelet-stimulating agents Eltrombopag systemic is used in the treatment of: Aplastic Anemia Idiopathic Thrombocytopenic Purpura Thrombocytopenia Thrombocytopenia Idiopathic Chemical structure Chemical structure of eltrombopag Further information GlaxoSmithKline has agreed to conduct trial TRA105325 entitled, EXTEND (Eltrombopag extended dosing study): an extension study of eltrombopag olamine in adults, with idiopathic thrombocytopenic purpura (ITP), previously enrolled in an eltrombopag study. File:Eltrombopag olamine.png. : VLST-00567. There are no contraindications for Eltrombopag. ; IC50 Value: 0.27 uM (EC50 in murine BAF3 cells) [1]; Target: thrombopoietin-receptor (c-mpl); Potential advantages of eltrombopag may include a sustained platelet response and a good. The objective of treatment with eltrombopag should not be to normalise platelet counts. - : . You are solely responsible for your interactions with that website. In case of an overdose, consider oral administration of a metal cation-containing preparation, such as Calcium, Aluminum, or Magnesium preparations to chelate Eltrombopag and thus limit absorption. If your organization : Eltrombopag Olamine. It is used in adults and in children aged 1 year or older with chronic immune thrombocytopenia (ITP). Eltrombopag c ch nh iu tr xut huyt gim tiu cu min dch (v cn) (immune (idiopathic) thrombocytopenic purpura - ITP) mn tnh bnh nhn ngi ln khng tr vi cc iu tr khc (v d corticosteroid, globulin min dch). : Elbonix. contact@vivanls.com. 2017;130(3):2527-2536. We uses SSL (standard security technology) to ensure data privacy of all our customers. Para qu es el medicamento? Preparation of eltrombopag bisethanolamine salt. Chemical Name. It does not require or replace the individual login accounts that many of you use to save searches and create email alerts. At right is a list of the countries that host a REVOLADE website based on local label Generic drugs generally cost less than brand name drugs. Monitor platelet counts regularly. Promacta (eltrombopag) is known as Revolade outside the U.S. and is marketed worldwide by Novartis. Initiate Eltrombopag at a dose of 50 mg once daily. ltrombopag is used to increase the number of platelets (cells that help the blood clot) to decrease the risk of bleeding in adults and children 1 year of age and older who have chronic immune thrombocytopenia (ITP; an ongoing condition that may cause unusual bruising or bleeding due to an abnormally low number of platelets in the blood) and who have not been helped or cannot be treated with other treatments, including medications or surgery to remove the spleen. Please contact your local Novartis representative for local ltrombopag is used to increase the number of platelets (cells that help the blood clot) to decrease the risk of bleeding in adults and children 1 year of age and older who have chronic immune thrombocytopenia (itp; an ongoing condition that may cause unusual bruising or bleeding due to an abnormally low number of platelets in the blood) and who Brand Name Dosage Form Strength Company Pack Size & Price; Cytopag . Documents - COA, HNMR, 13CNMR, MASS, HPLC (by pharmacopoeia method with RT RRT results), IR and TGA will be provided with the purchase of Eltrombopag Olamine is manufactured by ALLMPUS LABORATRIES PVT. Reduce the initial dose of Eltrombopag in patients with chronic ITP (adult and pediatric patients 6 years and older only) or severe aplastic anemia who also have hepatic impairment (Child-Pugh Class A, B, C). Hepatotoxicity: Monitor liver function before and during therapy. In animal reproduction and developmental toxicity studies, there was evidence ofembryolethality and reduced fetal weights at maternally toxic doses. In 73 healthy volunteers, higher doses of eltrombopag caused larger increases in the number of circulating platelets without tolerability problems Eltrombopag has been shown to be effective in two major clinical syndromes: idiopathic thrombocytopenic purpura (ITP) and cirrhosis due to hepatitis C(in which low platelet counts may be a contraindication for interferon treatment). Example 2. To gain full access to the content and functionality of the AdisInsight database try one of the following. Nursing Mothers: It is not known whether Eltrombopag is excreted in human milk. You have entered an incorrect email address! Eltrombopag Olamine, sold under the brand name Promacta among others, is a medication used to treat thrombocytopenia (abnormally low platelet counts) and severe aplastic anemia. How can I make sure I'm ordering the right brand to ensure I get a dairy and soy free medication? 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