Our mission is to support, not replace, the doctor-patient relationship. You must be registered in the program and sign documents stating that you understand the risks and benefits of taking this medication. Check the label on the medicine for exact dosing instructions. 7/18/2014. Very low platelet counts can lead to serious bleeding and bruising. The prescribed Romiplostim dose may consist of a very small volume (eg, 0.15 mL). Tell your doctor if any of these symptoms are severe or do not go away: headache joint or muscle pain pain in the arms, legs, or shoulders numbness, burning, or tingling in the arms or legs stomach pain heartburn vomiting diarrhea difficulty falling asleep or staying asleep They include but are not limited to policies relating to evolving medical technologies and procedures, as well as pharmacy policies. There was no detectable bone marrow collagen in one patient on repeat testing 12 weeks after discontinuation of Romiplostim. The information and contents of this website are for informational purposes only. They are not intended to be a substitute for professional medical advice, diagnosis, or treatment. Nplate J2796, injection, romiplostim, 10 mcg Nplate is supplied in single-use vials containing 125 mcg, 250 mcg and 500 mcg deliverable romiplostim The NDC numbers for Nplate, in the 11-digit format, are as follows: - 125-mcg vial: 55513-0223-01 - 250-mcg vial: 55513-0221-01 - 500-mcg vial: 55513-0222-01 Administration 96372, therapeutic . The safety and efficacy of romiplostim 250/500 mcg powder and solvent for solution for injection, also used for self-administration in eligible adult patients, have not been established in patients aged under 18 years. Withdraw the appropriate volume of the calculated dose from the vial. The data described below reflect Romiplostim exposure to 271 patients with chronic ITP, aged 18 to 88, of whom 62% were female. It is used to treat immune primary thrombocytopenia (called ITP). For example, a 75 kg patient initiating therapy at 1 mcg/kg will begin with a dose of 75 mcg. 3/11/2019. any questions, please ask your pharmacist. Site is running on IP address 34.210.113.179, host name ec2-34-210-113-179.us-west-2.compute.amazonaws.com (Boardman United States) ping response time 18ms Good ping.Current Global rank is 3,561,113, site estimated value 600$ Keep Romiset 250mcg Injection out of sight and reach of children. Find here Romiplostim Injection, Romy Injection suppliers, manufacturers, wholesalers, traders with Romiplostim Injection prices for buying. Douglas B.cines et al; Safety and efficacy of romiplostim in splenectomized and nonsplenectomized patients with primary immune thrombocytopenia; Haematologica; Published on August 2017; Accessed on 31/12/2021; You need to tell your physician if you have cancer, have recently had surgery or injury, or if you smoke. Romiplostim injection is used to increase the number of platelets (cells that help the blood to clot in order to decrease the risk of bleeding in adults who have immune thrombocytopenia (ITP; idiopathic thrombocytopenic purpura; an ongoing condition that may cause easy bruising or bleeding Interested in this product? Romiplostim may be used with other medical ITP therapies, such as corticosteroids, danazol, azathioprine, intravenous immunoglobulin (IVIG), and anti-D immunoglobulin. Nplate and Romiplate are available as injection (lyophilized powder) for subcutaneous use,. Reconstituted Romiplostim can be kept at room temperature (25C/77F) or refrigerated at 2 to 8C (36 to 46F) for up to 24 hours prior to administration. window.addEventListener('DOMContentLoaded', function() { Romy 250mcgInjection is not recommended for pregnant patients unless indicated by the doctor. https://www.medicines.org.uk/emc/files/pil.9325.pdf, https://www.accessdata.fda.gov/drugsatfda_docs/label/2018/125268s163lbl.pdf, https://www.haematologica.org/article/view/8154. Adult and pediatric dosage. Please tell your doctor and pharmacist about all the medicines you take. Do not suddenly stop taking this medicine. Obtain CBCs, including platelet counts, monthly thereafter. Romiplostim 250 MCG Injection is used to prevent bleeding episodes in people with chronic immune thrombocytopenic purpura (ITP), a bleeding condition caused by a lack of platelets in the blood. ** Use preservative-free Sterile Water for Injection. Following Information meant for Wholesalers, Suppliers, Exporters, Doctors, Comparator Supplies, Hospitals, Generic, Brand, Corporate Sourcing, reseller and Pharmacies. The general dosage of the medicine is using the lowest dose of medication to achieve and maintain a platelet count 50 109 /l as necessary to reduce the risk for bleeding. Super Quick Home Delivery with COD No Minimum Order Value Pan India Delivery . Females with childbearing potential must be advised to avoid becoming pregnant while on Romiplostim. NPLATE (ROMIPOSTIM) NPLATE is a prescription medicine used to treat low blood platelet counts (thrombocytopenia). Note:-The order will be confirmed only after the receipt of Valid prescription of Clinician. Facebook Twitter Linkedin Instagram. Nplate.com.This domain provided by markmonitor.com at 2008-01-12T19:51:35Z (14 Years, 176 Days ago), expired at 2024-01-12T19:51:35Z (1 Year, 189 Days left). SHARE THIS. IMPORTANT NOTE: This document tells you briefly how to take your medicine, but it does not tell you all As the injection volume may be very small, use a syringe with graduations to 0.01 mL. Romiplostim, a TPO mimetic class member, is an Fc-peptide fusion protein that activates intracellular transcriptional pathways leading to increased platelet production via the TPO receptor. Refer FAQs section for more details. If platelet count is > 200 x 109/L for 2 consecutive weeks, reduce the dose by 1 mcg/kg. WARNINGS AND PRECAUTIONS Patients who lacked response or lost response to Romiplostim or a non-US approved Romiplostim product were enrolled. If you notice any of these symptoms, seek medical help quickly. Symptoms of an allergic reaction can include trouble breathing, skin rash, itching, swelling, or severe dizziness. Administer Romiplostim as a weekly subcutaneous injection with dose adjustments based upon the platelet count response. Romiplostim is not indicated for the treatment of thrombocytopenia due to myelodysplastic syndrome (MDS) or any cause of thrombocytopenia other than chronic ITP. See also:What are the possible side effects of Romiplostim? Do not pool unused portions from the vials. This medicine will be given to you at the doctor's office. 250 mcg or 500 mcg of deliverable romiplostim in single-use vials ( 3) . https://www.medicines.org.uk/emc/files/pil.9325.pdf, https://www.accessdata.fda.gov/drugsatfda_docs/label/2018/125268s163lbl.pdf, https://www.haematologica.org/article/view/8154. Please seek the advice of your doctor and discuss all your queries related to any disease or medicine. Among 142 patients with chronic ITP who received Romiplostim in the single-arm extension study, the incidence rates of the adverse reactions occurred in a pattern similar to those reported in the placebo-controlled clinical studies. Generally, dissolution of Romiplostim takes less than 2 minutes. The information and contents of this website are for informational purposes only. Romiplostim should be used only in patients with ITP whose degree of thrombocytopenia and clinical condition increases the risk for bleeding. Please talk to them if you have any questions.Always follow their advice. Order romiset 250 mcg injection online today and save upto 75% on your medicine. 1 4/2/2018. Headache and respiratory tract infections are the most common side effects. Romiset 250mcg Injection stimulates the bone marrow (part of the bone that makes blood cells) to produce platelets and help prevent bruising and bleeding. Headache and respiratory tract infections are the most common side effects. MrMed is Indias largest super speciality pharmacy that delivers life saving medication at affordable prices. Uses. Each patient's dose will be determined based upon their actual body weight and platelet count at the time of dosing; Injection site irritation may occur; Romiplostim should NOT be given intravenously; Romiplostim should NOT be used to treat a . Romiplostim Injection 250 mcg September 24, 2021 . The reconstituted Romiplostim solution should be clear and colorless. Progression of bone marrow reticulin formation (increase greater than or equal to 2 grades or more) or an increase to Grade 4 (presence of collagen) was reported in 7% (9/131) of patients. Douglas B.cines et al; Safety and efficacy of romiplostim in splenectomized and nonsplenectomized patients with primary immune thrombocytopenia; Haematologica; Published on August 2017; Accessed on 31/12/2021; You need to tell your physician if you have cancer, have recently had surgery or injury, or if you smoke. ITP is a disorder in which the body's immune system destroys its own platelets, the blood cells which help seal cuts and form blood cuts. In case of overdose, platelet counts may increase excessively and result in thrombotic/thromboembolic complications, discontinue the medication administration, and keep the patient under observation. Romiplostim administration may increase the risk for development or progression of reticulin fiber formation within the bone marrow. Dose Adjustments Use the actual body weight at initiation of therapy, then adjust the weekly dose of Romiplostim by increments of 1 mcg/kg until the patient achieves a platelet count 50 x 109/L as necessary to reduce the risk for bleeding; do not exceed a maximum . The majority of these adverse drug reactions were mild to moderate in severity. We maintain strict quality controls on all our partner retailers, so that you always get standard quality products. The incidence of preexisting antibodies to endogenous TPO was 4% (40/1112) and the incidence of binding antibody development to endogenous TPO during treatment was 3% (38/1112). Do not disregard professional medical advice or delay in seeking it because of something you have read on MrMed. Continue to assess the platelet count weekly. One patient was positive for binding antibodies to both Romiplostim and TPO. Overall, Romiplostim was administered to 114 patients for at least 52 weeks and 53 patients for at least 96 weeks. Used to treat thrombocytopenia associated with chronic immune thrombocytopenia (ITP). With the launch of Romy, which is priced at Rs. 1 12/12/2016. Calculate the dose and reconstitute with the correct volume of sterile water for injection. Enter the email address you signed up with and we'll email you a reset link. Most common side effects of Romiplostim are Joint pain, difficulty in sleeping, dizziness, Muscle pain, Pain in extremity, Abdominal pain, Indigestion, headache and tingling or pricking sensation. Check with your doctor before stopping. The initial dose for Romiplostim is 1 mcg/kg based on actual body weight. Talk with your doctor if you have any bruising or bleeding episodes after 4 weeks of treatment. Please seek the advice of your doctor and discuss all your queries related to any disease or medicine. Romiplostim should protect from light and retain in the original carton until use. Romy 250mcgInjection is not recommended for breastfeeding patients. Each mL contains 250 mcg teriparatide (as a free base), 0.41 mg glacial acetic acid, 0.10 mg sodium acetate, 45.4 mg mannitol, 3 mg metacresol, and water for injection. 8% OFF. Romiplostim injection comes as a powder to be mixed with liquid to be injected subcutaneously under the supervision of an experienced healthcare provider. 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