eltrombopag. Learn about Diovan (valsartan), potential side effects, proper use and dosing, and popular alternatives. Tranexamic acid is a synthetic analog of the amino acid lysine.It serves as an antifibrinolytic by reversibly binding four to five lysine receptor sites on plasminogen.This decreases the conversion of plasminogen to plasmin, preventing fibrin degradation and preserving the framework of fibrin's matrix structure. Use Caution/Monitor. The serum concentration of Eltrombopag can be increased when it is combined with Abiraterone. Verapamil is commonly used off-label for prophylaxis of cluster headaches. Follow all directions on your prescription label and read all medication guides or instruction sheets. Reduce drug development failure rates. Indicated as an adjunct to diet to reduce total-C, LDL-C, and apo B levels in boys and postmenarchal girls aged 10-17 years with HeFH who have an inadequate response to diet alone (ie, LDL-C remains 190 mg/dL or LDL-C remains 160 mg/dL and there is positive family history or early CV disease or 2 or more other CVD risk factors present) You may report side effects to FDA at 1-800-FDA-1088. LB-502; NSC-269420; Pharmacology Indication. Initial U.S. Approval: 2008 . The following information includes only the average doses of this medicine. The following information includes only the average doses of this medicine. You may report side effects to FDA at 1-800-FDA-1088. The serum concentration of Eltrombopag can be increased when it is combined with Abiraterone. Heterozygous Familial Hypercholesterolemia. Patients were permitted to treat up to 8 migraines per month with UBRELVY. Complementary & Alternative Medicine (CAM) CAM for Patients. Recently, one of the two thrombopoietin-receptor agonists, eltrombopag, was investigated as a possible treatment option in MYH9-related disorders (May-Hegglin anomaly associated with the MYH9 gene) (FDA) in 2008 and have as results of the long-term, open-label EXTEND study. Off-Label Drug Use. Nifedipine, or BAY a 1040, is a first generation dihydropyridine L-type calcium channel blocker, similar to nicardipine. Acne Vulgaris (Off-label) 1 DS tab or 1 regular-strength tab PO qDay or q12hr for up to 18 weeks. eltrombopag will decrease the level or effect of valsartan by Other (see comment). Drug Induced Liver Injury Rank (DILIrank) consists of 1,036 FDA-approved drugs that are divided into four classes according to their potential for causing drug-induced liver injury (DILI) 6 It was first described in the literature in 2003 when Chugai, a subsidiary of Roche began developing IL-6 inhibiting monoclonal antibodies. See full prescribing information for complete boxed warning . Eltrombopag leads to a reduction in free intracellular iron in leukemic cells in a dose-dependent manner in HL60 cells. Sign Up The metabolism of Eltrombopag can be decreased when combined with Diltiazem. Hydrofluoric Acid Burn (Off-label) Immediately irrigate skin with tap water; lavage should occur immediately at hydrofluoric acid burn site for 15-30 min After irrigation, apply calcium gluconate 2.5-5% gel to the affected area q30min initially, then q4hr afterwards for ~3-4 days Telmisartan is an orally active nonpeptide angiotensin II antagonist that acts on the AT 1 receptor subtype. Promacta (Eltrombopag Olamine) Propranolol Hydrochloride; Provenge (Sipuleucel-T) Purinethol (Mercaptopurine) Purixan (Mercaptopurine) Q. Qinlock (Ripretinib) R. exenatide injectable solution. dosing intermittently for up to 1 year in an open-label extension study. 20-40 mg/kg/day IV/PO divided q6hr . 20-40 mg/kg/day IV/PO divided q6hr . Long-term safety was assessed in 813 patients, dosing intermittently for up to 1-year in an open-label extension study. For oral use. It is a narcotic antagonist that is effective orally, longer lasting and more potent than naloxone, and has been proposed for the treatment of heroin addiction. Learn about dicyclomine, potential side effects, proper use and dosing, and popular alternatives. You take mineral or vitamin supplements: If zinc is taken at the same time, it can decrease the absorption and effectiveness of these supplements. Community Acquired Pneumonia (Off-label) 1 DS tab PO q12hr for 10-14 days. Generic Name Tocilizumab DrugBank Accession Number DB06273 Background. Generic Name Nifedipine DrugBank Accession Number DB01115 Background. Neonates (28 days old): 5-20 mg/kg/day IV/PO divided q8-12hr eltrombopag. Ubrelvy side effects (more detail) eltrombopag; fluconazole; fluvoxamine; phenytoin; St. John's wort; doi: 10.1182/blood-2012-04-425512. aminotransferase (AST), and bilirubin prior to initiation of Use Caution/Monitor. 6 It was first described in the literature in 2003 when Chugai, a subsidiary of Roche began developing IL-6 inhibiting monoclonal antibodies. Use the medicine exactly as directed. The following information includes only the average doses of this medicine. Use Caution/Monitor. Phase Status Purpose Conditions Count; 4: You may report side effects to FDA at 1-800-FDA-1088. Your doctor may occasionally change your dose. Pharmacodynamics. Derivative of noroxymorphone that is the N-cyclopropylmethyl congener of naloxone. eltrombopag will decrease the level or effect of valsartan by Other (see comment). Recently, one of the two thrombopoietin-receptor agonists, eltrombopag, was investigated as a possible treatment option in MYH9-related disorders (May-Hegglin anomaly associated with the MYH9 gene) (FDA) in 2008 and have as results of the long-term, open-label EXTEND study. Of these 813 patients, 421 patients were exposed to 50 mg or 100 mg for at least 6 months, and 364 patients were exposed to these CAM for Health Professionals. CAM for Health Professionals. Follow all directions on your prescription label and read all medication guides or instruction sheets. It is a narcotic antagonist that is effective orally, longer lasting and more potent than naloxone, and has been proposed for the treatment of heroin addiction. Use Caution/Monitor. eltrombopag. Telmisartan is an orally active nonpeptide angiotensin II antagonist that acts on the AT 1 receptor subtype. Complementary & Alternative Medicine (CAM) CAM for Patients. 2 Tocilizumab was granted 10 Significant fetal transfer occurs with enalapril and enalaprilat thus the use of the drug in pregnant women should be strongly avoided. Tranexamic acid has roughly eight times the Use Caution/Monitor. Blood. Off-Label Drug Use. Sign Up Duodenal Ulcer (Off-label) 16 years: Use only if benefit outweighs risks. Label As enalapril and enalaprilat were shown to be secreted in human milk in trace amounts, the use of enalaprilat in nursing women is not recommended. Mechanism of action. You are taking drugs like penicillamine or eltrombopag for rare disorders such as Wilsons disease or chronic autoimmune thrombocytopenia: The effectiveness of these drugs can be greatly reduced. Patients were permitted to treat up to 8 migraines per month with UBRELVY. Off-label. If your dose is different, do not change it unless your doctor tells you to do so. 2013; 121:53745. Nifedipine, or BAY a 1040, is a first generation dihydropyridine L-type calcium channel blocker, similar to nicardipine. Off-label. doi: 10.1182/blood-2012-04-425512. Eltrombopag leads to a reduction in free intracellular iron in leukemic cells in a dose-dependent manner in HL60 cells. Pharmacodynamics. 3,10,11,13 Nifedipine was developed by Bayer and first described in the literature, along with other dihydropyridines, in 1972. Ubrelvy side effects (more detail) eltrombopag; fluconazole; fluvoxamine; phenytoin; St. John's wort; In an open-label, forced-titration study, homozygous FH patients (n=40, 8-63 years) were evaluated for their response to rosuvastatin calcium 20 to 40 mg titrated at a 6-week interval. 4. fluvoxamine will increase the level or effect of eltrombopag by affecting hepatic enzyme CYP1A2 metabolism. Clinical drug interaction studies with inhibitors of these transporters were not conducted. You may report side effects to FDA at 1-800-FDA-1088. Sign Up Follow all directions on your prescription label and read all medication guides or instruction sheets. Off-label. If your dose is different, do not change it unless your doctor tells you to do so. Download (480 KB) Clinical Trials Clinical Trials . Password requirements: 6 to 30 characters long; ASCII characters only (characters found on a standard US keyboard); must contain at least 4 different symbols; 2013; 121:53745. DESCRIPTION. Eltrombopag (5 g/mL) causes an increase in CD11b, which is consistent with a premacrophage state in U937 cells, and also causes an increase in CD11b in URE cells. eltrombopag. Ubrogepant is a substrate of BCRP and P-gp efflux transporters. Type Small Molecule Groups aminotransferase (AST), and bilirubin prior to initiation of The metabolism of Verapamil can be decreased when combined with Eltrombopag. eltrombopag. Patients were permitted to treat up to 8 migraines per month with UBRELVY. Complementary & Alternative Medicine (CAM) CAM for Patients. Ubrogepant is a substrate of BCRP and P-gp efflux transporters. Moderately Severe Acute Pain (Off-label) 2 years. Clinical drug interaction studies with inhibitors of these transporters were not conducted. Use Caution/Monitor. 3,10,11,13 Nifedipine was developed by Bayer and first described in the literature, along with other dihydropyridines, in 1972. New studies suggest that telmisartan may also have PPAR agonistic properties that could potentially confer beneficial metabolic Patients were permitted to treat up to 8 migraines per month with UBRELVY. Tocilizumab is a recombinant humanized monoclonal antibody IL-6 receptor inhibitor used to treat inflammatory and autoimmune conditions. Loading dose: 4-6 g IV over 20 minutes; maintenance: 2-4 g/hr IV for 12-24 hours as tolerated after contractions cease eltrombopag. In an open-label, forced-titration study, homozygous FH patients (n=40, 8-63 years) were evaluated for their response to rosuvastatin calcium 20 to 40 mg titrated at a 6-week interval. For oral use. Your doctor may occasionally change your dose. Of these 813 patients, 421 patients were exposed to 50 mg or 100 mg for at least 6 months, and 364 patients were exposed to these Download (418 KB) MSDS. Long-term safety was assessed in 813 patients, dosing intermittently for up to 1-year in an open-label extension study. Password requirements: 6 to 30 characters long; ASCII characters only (characters found on a standard US keyboard); must contain at least 4 different symbols; It has the highest affinity for the AT 1 receptor among commercially available ARBS and has minimal affinity for the AT 2 receptor. Off-Label Drug Use. Mechanism of action. You may report side effects to FDA at 1-800-FDA-1088. Furosemide is indicated for the treatment of edema associated with congestive heart failure, cirrhosis of the liver, and renal disease, including the nephrotic syndrome, in adults and pediatric patients. WARNING: RISK FOR HEPATOTOXICITY . 9 Oral furosemide is indicated alone for the management of mild to moderate hypertension or severe hypertension in combination with You take mineral or vitamin supplements: If zinc is taken at the same time, it can decrease the absorption and effectiveness of these supplements. Use of BCRP and/or P-gp only inhibitors (e.g., quinidine, carvedilol, eltrombopag, curcumin) may increase the exposure of ubrogepant [s ee Clinical Pharmacology ]. Moderately Severe Acute Pain (Off-label) 2 years. The FDA has approved naltrexone for the treatment of alcohol dependence. Type Small Molecule Groups FDA label. See full prescribing information for complete boxed warning . Learn about Diovan (valsartan), potential side effects, proper use and dosing, and popular alternatives. You may report side effects to FDA at 1-800-FDA-1088. In an open-label, forced-titration study, homozygous FH patients (n=40, 8-63 years) were evaluated for their response to rosuvastatin calcium 20 to 40 mg titrated at a 6-week interval. {{configCtrl2.info.metaDescription}} Sign up today to receive the latest news and updates from UpToDate. You may report side effects to FDA at 1-800-FDA-1088. aminotransferase (AST), and bilirubin prior to initiation of New studies suggest that telmisartan may also have PPAR agonistic properties that could potentially confer beneficial metabolic Derivative of noroxymorphone that is the N-cyclopropylmethyl congener of naloxone. Duodenal Ulcer (Off-label) 16 years: Use only if benefit outweighs risks. Moderately Severe Acute Pain (Off-label) 2 years. Read reviews from GoodRx users who have taken Diovan (valsartan) and find the latest news on the drug. Approved in 1982 by the FDA, it is a member of the non-dihydropyridine calcium channel blockers drug class. Mechanism of action. Eltrombopag (5 g/mL) causes an increase in CD11b, which is consistent with a premacrophage state in U937 cells, and also causes an increase in CD11b in URE cells. Read reviews from GoodRx users who have taken Diovan (valsartan) and find the latest news on the drug. Read reviews from GoodRx users who have taken dicyclomine and find the latest news on the drug. Tranexamic acid is a synthetic analog of the amino acid lysine.It serves as an antifibrinolytic by reversibly binding four to five lysine receptor sites on plasminogen.This decreases the conversion of plasminogen to plasmin, preventing fibrin degradation and preserving the framework of fibrin's matrix structure. The serum concentration of Eltrombopag can be increased when it is combined with Abiraterone. CAM for Health Professionals. Use the medicine exactly as directed. If your dose is different, do not change it unless your doctor tells you to do so. exenatide injectable solution will decrease the level or effect of acetaminophen by unspecified interaction mechanism. It causes a characteristic red or purple bruise-like rash and an increased tendency to bleed. 2 Tocilizumab was granted Verapamil is commonly used off-label for prophylaxis of cluster headaches. Heterozygous Familial Hypercholesterolemia. Elvitegravir: Eltrombopag leads to a reduction in free intracellular iron in leukemic cells in a dose-dependent manner in HL60 cells. It causes a characteristic red or purple bruise-like rash and an increased tendency to bleed. You may report side effects to FDA at 1-800-FDA-1088. The FDA has approved naltrexone for the treatment of alcohol dependence. eltrombopag. doi: 10.1182/blood-2012-04-425512. Use Caution/Monitor. exenatide injectable solution. It causes a characteristic red or purple bruise-like rash and an increased tendency to bleed. eltrombopag. Generic Name Nifedipine DrugBank Accession Number DB01115 Background. Tocilizumab is a recombinant humanized monoclonal antibody IL-6 receptor inhibitor used to treat inflammatory and autoimmune conditions. {{configCtrl2.info.metaDescription}} Sign up today to receive the latest news and updates from UpToDate. 9 Oral furosemide is indicated alone for the management of mild to moderate hypertension or severe hypertension in combination with 3,10,11,13 Nifedipine was developed by Bayer and first described in the literature, along with other dihydropyridines, in 1972. Generic Name Tocilizumab DrugBank Accession Number DB06273 Background. Physician reviewed eltrombopag patient information - includes eltrombopag description, dosage and directions. Neonates (28 days old): 5-20 mg/kg/day IV/PO divided q8-12hr eltrombopag. Immune thrombocytopenic purpura (ITP), also known as idiopathic thrombocytopenic purpura or immune thrombocytopenia, is a type of thrombocytopenic purpura defined as an isolated low platelet count with a normal bone marrow in the absence of other causes of low platelets. Ubrogepant is a substrate of BCRP and P-gp efflux transporters. Duodenal Ulcer (Off-label) 16 years: Use only if benefit outweighs risks. 4. sulfamethoxazole will increase the level or effect of eltrombopag by affecting hepatic enzyme CYP2C9/10 metabolism. Follow your doctor's orders or the directions on the label. Expand current row for information about eltrombopag eltrombopag: 5.0 2 reviews: Rx: C N: Off-label: This medication may not be approved by the FDA for the treatment of this condition. Read reviews from GoodRx users who have taken dicyclomine and find the latest news on the drug. Long-term safety was assessed in 813 patients, dosing intermittently for up to 1-year in an open-label extension study. The metabolism of Verapamil can be decreased when combined with Eltrombopag. Access to Experimental Drugs. Heterozygous Familial Hypercholesterolemia. Ubrelvy side effects (more detail) eltrombopag; fluconazole; fluvoxamine; phenytoin; St. John's wort; Preterm Labor (Off-label) Used as a tocolytic to stop preterm labor. It is a narcotic antagonist that is effective orally, longer lasting and more potent than naloxone, and has been proposed for the treatment of heroin addiction. DESCRIPTION. PROMACTA may cause hepatotoxicity: Measure serum alanine aminotransferase (ALT), aspartate . cimetidine will increase the level or effect of eltrombopag by affecting hepatic enzyme CYP1A2 metabolism. Physician reviewed eltrombopag patient information - includes eltrombopag description, dosage and directions. eltrombopag. fluvoxamine will increase the level or effect of eltrombopag by affecting hepatic enzyme CYP1A2 metabolism. WARNING: RISK FOR HEPATOTOXICITY . Neonates (28 days old): 5-20 mg/kg/day IV/PO divided q8-12hr eltrombopag. Label As enalapril and enalaprilat were shown to be secreted in human milk in trace amounts, the use of enalaprilat in nursing women is not recommended. Derivative of noroxymorphone that is the N-cyclopropylmethyl congener of naloxone. Follow all directions on your prescription label and read all medication guides or instruction sheets. Access to Experimental Drugs. Drug Induced Liver Injury Rank (DILIrank) consists of 1,036 FDA-approved drugs that are divided into four classes according to their potential for causing drug-induced liver injury (DILI) Initial U.S. Approval: 2008 . cimetidine will increase the level or effect of eltrombopag by affecting hepatic enzyme CYP1A2 metabolism. cimetidine will increase the level or effect of eltrombopag by affecting hepatic enzyme CYP1A2 metabolism. Read reviews from GoodRx users who have taken dicyclomine and find the latest news on the drug. The metabolism of Eltrombopag can be decreased when combined with Diltiazem. UGT inhibition; significance of interaction unclear. WARNING: RISK FOR HEPATOTOXICITY . eltrombopag increases levels of acetaminophen by decreasing metabolism. Access to Experimental Drugs. The FDA has approved naltrexone for the treatment of alcohol dependence. Download (418 KB) MSDS. Follow all directions on your prescription label and read all medication guides or instruction sheets. Elvitegravir: Download (418 KB) MSDS. Promacta (Eltrombopag Olamine) Propranolol Hydrochloride; Provenge (Sipuleucel-T) Purinethol (Mercaptopurine) Purixan (Mercaptopurine) Q. Qinlock (Ripretinib) R. Immune thrombocytopenic purpura (ITP), also known as idiopathic thrombocytopenic purpura or immune thrombocytopenia, is a type of thrombocytopenic purpura defined as an isolated low platelet count with a normal bone marrow in the absence of other causes of low platelets. Label As enalapril and enalaprilat were shown to be secreted in human milk in trace amounts, the use of enalaprilat in nursing women is not recommended. {{configCtrl2.info.metaDescription}} Sign up today to receive the latest news and updates from UpToDate. Download (480 KB) Clinical Trials Clinical Trials . Preterm Labor (Off-label) Used as a tocolytic to stop preterm labor. Generic Name Tocilizumab DrugBank Accession Number DB06273 Background. Use Caution/Monitor. Elvitegravir: The metabolism of Eltrombopag can be decreased when combined with Diltiazem. Elvitegravir: The metabolism of Abiraterone can be decreased when combined with Elvitegravir. magnesium sulfate decreases levels of eltrombopag by inhibition of GI absorption. Indicated as an adjunct to diet to reduce total-C, LDL-C, and apo B levels in boys and postmenarchal girls aged 10-17 years with HeFH who have an inadequate response to diet alone (ie, LDL-C remains 190 mg/dL or LDL-C remains 160 mg/dL and there is positive family history or early CV disease or 2 or more other CVD risk factors present) eltrombopag increases levels of acetaminophen by decreasing metabolism. eltrombopag. You are taking drugs like penicillamine or eltrombopag for rare disorders such as Wilsons disease or chronic autoimmune thrombocytopenia: The effectiveness of these drugs can be greatly reduced. exenatide injectable solution. Phase Status Purpose Conditions Count; 4: Type Small Molecule Groups Acne Vulgaris (Off-label) 1 DS tab or 1 regular-strength tab PO qDay or q12hr for up to 18 weeks. Download (480 KB) Clinical Trials Clinical Trials . Password requirements: 6 to 30 characters long; ASCII characters only (characters found on a standard US keyboard); must contain at least 4 different symbols; Expand current row for information about eltrombopag eltrombopag: 5.0 2 reviews: Rx: C N: Off-label: This medication may not be approved by the FDA for the treatment of this condition. Approved in 1982 by the FDA, it is a member of the non-dihydropyridine calcium channel blockers drug class. Patients were permitted to treat up to 8 migraines per month with UBRELVY. Learn about Diovan (valsartan), potential side effects, proper use and dosing, and popular alternatives. See full prescribing information for complete boxed warning . DESCRIPTION. You may report side effects to FDA at 1-800-FDA-1088. 6 It was first described in the literature in 2003 when Chugai, a subsidiary of Roche began developing IL-6 inhibiting monoclonal antibodies. Use Caution/Monitor. Eltrombopag (5 g/mL) causes an increase in CD11b, which is consistent with a premacrophage state in U937 cells, and also causes an increase in CD11b in URE cells. a substrate of BCRP and P-gp efflux transporters. Nifedipine, or BAY a 1040, is a first generation dihydropyridine L-type calcium channel blocker, similar to nicardipine. Tranexamic acid is a synthetic analog of the amino acid lysine.It serves as an antifibrinolytic by reversibly binding four to five lysine receptor sites on plasminogen.This decreases the conversion of plasminogen to plasmin, preventing fibrin degradation and preserving the framework of fibrin's matrix structure. eltrombopag increases levels of acetaminophen by decreasing metabolism. Follow your doctor's orders or the directions on the label. Safety and efficacy not established; 2-16 years. Safety and efficacy not established; 2-16 years. a substrate of BCRP and P-gp efflux transporters. Physician reviewed eltrombopag patient information - includes eltrombopag description, dosage and directions. It has the highest affinity for the AT 1 receptor among commercially available ARBS and has minimal affinity for the AT 2 receptor. LB-502; NSC-269420; Pharmacology Indication. dosing intermittently for up to 1 year in an open-label extension study. PROMACTA may cause hepatotoxicity: Measure serum alanine aminotransferase (ALT), aspartate . Use of BCRP and/or P-gp only inhibitors (e.g., quinidine, carvedilol, eltrombopag, curcumin) may increase the exposure of ubrogepant [s ee Clinical Pharmacology ]. Tranexamic acid has roughly eight times the Furosemide is indicated for the treatment of edema associated with congestive heart failure, cirrhosis of the liver, and renal disease, including the nephrotic syndrome, in adults and pediatric patients. Indicated as an adjunct to diet to reduce total-C, LDL-C, and apo B levels in boys and postmenarchal girls aged 10-17 years with HeFH who have an inadequate response to diet alone (ie, LDL-C remains 190 mg/dL or LDL-C remains 160 mg/dL and there is positive family history or early CV disease or 2 or more other CVD risk factors present) Panic Disorder (Off-label) 25-50 mg PO qDay; after several days, gradually increase to 100-200 mg/day; may increase to 300 mg/day for patients who fail to respond after several weeks of treatment eltrombopag. 10 Significant fetal transfer occurs with enalapril and enalaprilat thus the use of the drug in pregnant women should be strongly avoided. Drug Induced Liver Injury Rank (DILIrank) consists of 1,036 FDA-approved drugs that are divided into four classes according to their potential for causing drug-induced liver injury (DILI) UGT inhibition; significance of interaction unclear. It has the highest affinity for the AT 1 receptor among commercially available ARBS and has minimal affinity for the AT 2 receptor. exenatide injectable solution will decrease the level or effect of acetaminophen by unspecified interaction mechanism. Use the medicine exactly as directed. Pharmacodynamics. Read reviews from GoodRx users who have taken Diovan (valsartan) and find the latest news on the drug. 2013; 121:53745. Of these 813 patients, 421 patients were exposed to 50 mg or 100 mg for at least 6 months, and 364 patients were exposed to these FDA label. 20-40 mg/kg/day IV/PO divided q6hr . Initial U.S. Approval: 2008 . Use of BCRP and/or P-gp only inhibitors (e.g., quinidine, carvedilol, eltrombopag, curcumin) may increase the exposure of ubrogepant [s ee Clinical Pharmacology ]. Hydrofluoric Acid Burn (Off-label) Immediately irrigate skin with tap water; lavage should occur immediately at hydrofluoric acid burn site for 15-30 min After irrigation, apply calcium gluconate 2.5-5% gel to the affected area q30min initially, then q4hr afterwards for ~3-4 days FDA label. Community Acquired Pneumonia (Off-label) 1 DS tab PO q12hr for 10-14 days. Tocilizumab is a recombinant humanized monoclonal antibody IL-6 receptor inhibitor used to treat inflammatory and autoimmune conditions. Elvitegravir: The metabolism of Abiraterone can be decreased when combined with Elvitegravir. You may report side effects to FDA at 1-800-FDA-1088. sulfamethoxazole will increase the level or effect of eltrombopag by affecting hepatic enzyme CYP2C9/10 metabolism. Safety and efficacy not established; 2-16 years. PROMACTA (eltrombopag) Tablets . Generic Name Nifedipine DrugBank Accession Number DB01115 Background. You are taking drugs like penicillamine or eltrombopag for rare disorders such as Wilsons disease or chronic autoimmune thrombocytopenia: The effectiveness of these drugs can be greatly reduced. UGT inhibition; significance of interaction unclear. Immune thrombocytopenic purpura (ITP), also known as idiopathic thrombocytopenic purpura or immune thrombocytopenia, is a type of thrombocytopenic purpura defined as an isolated low platelet count with a normal bone marrow in the absence of other causes of low platelets.
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